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Karl Zilles Selected Research

Neurotransmitter Receptors (Neurotransmitter Receptor)

1/2022Personalized brain models identify neurotransmitter receptor changes in Alzheimer's disease.
4/2020Multimodal mapping and analysis of the cyto- and receptorarchitecture of the human hippocampus.
8/2013Neurotransmitter receptor alterations in hepatic encephalopathy: a review.
8/2010Inhibition of glutamate/glutamine cycle in vivo results in decreased benzodiazepine binding and differentially regulated GABAergic subunit expression in the rat brain.
1/2009Neurotransmitter receptor imbalances in motor cortex and basal ganglia in hepatic encephalopathy.
8/2005Regional and subtype selective changes of neurotransmitter receptor density in a rat transgenic for the Huntington's disease mutation.

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Karl Zilles Research Topics

Disease

6Hepatic Encephalopathy
08/2013 - 05/2002
6Glioma (Gliomas)
05/2013 - 07/2003
5Neoplasms (Cancer)
05/2013 - 07/2003
2Alzheimer Disease (Alzheimer's Disease)
01/2022 - 02/2018
2Parkinson Disease (Parkinson's Disease)
01/2018 - 01/2018
2Infarction (Infarctions)
05/2013 - 03/2006
2Epilepsy (Aura)
08/2010 - 10/2008
2Fibrosis (Cirrhosis)
07/2010 - 03/2008
2Seizures (Absence Seizure)
10/2008 - 07/2005
2Liver Cirrhosis (Hepatic Cirrhosis)
03/2008 - 10/2006
2Schizophrenia (Dementia Praecox)
01/2008 - 12/2005
2Stroke (Strokes)
03/2006 - 01/2003
1Clinical Deterioration
01/2022
1Shock
04/2020
1Temporal Lobe Epilepsy
10/2018
1Dementia (Dementias)
07/2015
1Partial Epilepsies (Epilepsy, Partial)
11/2012
1Mood Disorders (Mood Disorder)
03/2012
1Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome)
06/2009
1Lipoid Proteinosis of Urbach and Wiethe (Lipoidproteinosis)
03/2009
1Motor Disorders
04/2008
1Glioblastoma (Glioblastoma Multiforme)
01/2008
1Sleep Deprivation
02/2007
1Brain Ischemia (Cerebral Ischemia)
03/2006
1Prodromal Symptoms
12/2005
1Neurodegenerative Diseases (Neurodegenerative Disease)
08/2005
1Huntington Disease (Huntington's Disease)
08/2005
1Ischemia
12/2004
1Body Weight (Weight, Body)
12/2004
1Gliosis
12/2004

Drug/Important Bio-Agent (IBA)

6Neurotransmitter Receptors (Neurotransmitter Receptor)IBA
01/2022 - 08/2005
4Tyrosine (L-Tyrosine)FDA Link
07/2010 - 07/2003
4Purinergic P1 Receptors (Adenosine Receptor)IBA
03/2008 - 03/2005
3Pentylenetetrazole (Metrazol)IBA
08/2010 - 07/2005
3Neurotransmitter Agents (Neurotransmitter)IBA
06/2009 - 03/2008
3Indicators and Reagents (Reagents)IBA
01/2008 - 03/2005
2Biological ProductsIBA
01/2022 - 01/2008
2Cholinergic Agents (Cholinergics)IBA
01/2018 - 08/2005
2altanserinIBA
03/2009 - 12/2005
25-HT2A Serotonin Receptor (5 HT2A Receptor)IBA
03/2009 - 12/2005
1Amyloid (Amyloid Fibrils)IBA
01/2022
1Cholinergic ReceptorsIBA
01/2022
1Pharmaceutical PreparationsIBA
01/2022
1N-Ethylmaleimide-Sensitive Proteins (N-Ethylmaleimide-Sensitive Fusion Protein)IBA
10/2018
1Staphylococcal Protein A (Protein A)IBA
10/2018
1Type A Botulinum Toxins (Botox)FDA Link
01/2018
1incobotulinumtoxinAFDA Link
01/2018
1Proline (L-Proline)FDA Link
05/2013
1LigandsIBA
11/2012
1Messenger RNA (mRNA)IBA
11/2010
1RNA (Ribonucleic Acid)IBA
07/2010
18-hydroxyguanosineIBA
07/2010
1Proteins (Proteins, Gene)FDA Link
07/2010
1Glutamate-Ammonia Ligase (Glutamine Synthetase)IBA
10/2008
1ElementsIBA
01/2008
1CopperIBA
01/2008
1ZincIBA
01/2008
18- cyclopenta- 3- (3- fluoropropyl)- 1- propylxanthineIBA
02/2007
1Fluvoxamine (Luvox)FDA LinkGeneric
10/2006
1CytochromesIBA
10/2006
1Cytochrome P-450 CYP1A2 (CYP1A2)IBA
10/2006
1Antidepressive Agents (Antidepressants)IBA
10/2006
1Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA
03/2006
1SolventsIBA
03/2006
1Cyclooxygenase 2 (Cyclooxygenase-2)IBA
03/2006
1Antipsychotic Agents (Antipsychotics)IBA
12/2005
1Huntingtin ProteinIBA
08/2005
1polyglutamineIBA
08/2005
1Adenosine (Adenocard)FDA LinkGeneric
03/2005
1Heme Oxygenase-1IBA
12/2004
1Glial Fibrillary Acidic ProteinIBA
12/2004
1ManganeseIBA
11/2003
1Methionine (L-Methionine)FDA Link
07/2003
1gamma-Aminobutyric Acid (GABA)IBA
01/2003
1Butyric Acid (Butanoic Acid)IBA
01/2003
1AmmoniaIBA
05/2002

Therapy/Procedure

2Deep Brain Stimulation
02/2018 - 07/2015
1Therapeutics
03/2012
1Laser Therapy (Surgery, Laser)
01/2008